An estimated 3 - 8% of women of reproductive age have PMDD. This number does not account for missed or misdiagnosis nor women whose ovulatory cycle is suppressed by hormonal, chemical, or surgical means. Criteria for diagnosis set by The American Psychological Association (APA) and The International Society for Premenstrual Disorders (ISPMD) also exclude women with co-existing physiological or physical disorder.
There are an estimated 62,549,428 women of reproductive age living in the United States (ages 15 - 44) which means an estimated 5 million women in the United States are living with PMDD.
15% of women with PMDD will commit an act of suicide in their lifetime. For every male that dies by suicide, four women attempt it.
Women experience depression at roughly twice the rate of men. Many factors in women may contribute to depression, such as developmental, reproductive, hormonal, genetic and other biological differences (e.g. premenstrual syndrome, childbirth, infertility, and menopause).