An estimated 3 - 8% of women of reproductive age have PMDD.  This number does not account for missed or misdiagnosis nor women whose ovulatory cycle is suppressed by hormonal, chemical, or surgical means. Criteria for diagnosis set by The American Psychological Association (APA) and The International Society for Premenstrual Disorders (ISPMD) also exclude women with co-existing physiological or physical disorder.

Prevalence In Women of Reproductive Age
 
 

There are an estimated 62,549,428 women of reproductive age living in the United States (ages 15 - 44) which means an estimated 5 million women in the United States are living with PMDD.

15% of women with PMDD will commit an act of suicide in their lifetime. For every male that dies by suicide, four women attempt it.

Women experience depression at roughly twice the rate of men. Many factors in women may contribute to depression, such as developmental, reproductive, hormonal, genetic and other biological differences (e.g. premenstrual syndrome, childbirth, infertility, and menopause).

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References

1. Guttmacher Data Center Guttmacher Data Center. (2016). Data.guttmacher.org. Retrieved 13 April 2016, from https://data.guttmacher.org/states/table?state=US&topics=150&dataset=data#source
2. Cunningham J, Yonkers KA, O’Brien S, Eriksson E. Update on Research and Treatment of Premenstrual Dysphoric Disorder. Harvard review of psychiatry. 2009;17(2):120-137. doi:10.1080/10673220902891836.
3. Suicide Statistics - AFSP Suicide Statistics - AFSP. (2016). AFSP. Retrieved 13 April 2016, from Patient Advocacy & Peer Support
4. DeMuth, W. (2016). Premenstrual Syndrome and Premenstrual Dysphoric Disorder - American Family Physician. Aafp.org. Retrieved 13 April 2016, from http://www.aafp.org/afp/2011/1015/p918.html
6. (2016). Depression In Women. Mental Health America. Retrieved 14 April 2016, from http://www.mentalhealthamerica.net/conditions/depression-women